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Dr. Amy Ryan

Assistant Professor of Biological Sciences

I am a neurobiologist by training, with specific interest in the cellular mechanisms of neurodegeneration. My Ph.D. project focused on the pathogenesis of Huntington’s disease and the involvement of the tumor suppressor protein, p53, in disease progression. During my postdoctoral training, I studied the role of DNA damage in Alzheimer’s disease and in normal brain aging. I am currently researching the deleterious effects of Huntington’s disease in peripheral tissues, such as the pancreas.





  • Ph.D. in Neuroscience, University of Virginia
  • B.S. in Cellular Biochemistry, SUNY Plattsburgh

Teaching Areas

  • Bio100/Bio103 Concepts in Biology
  • Bio101 General Biology Labs
  • Bio380 Communicating Biology
  • Bio387 Neurobiology

Research Areas

  • Mechanisms of Neurodegeneration

Selected Publications

  • Stevenson, M., Carlisle, R., Davies, B., Preece, C., Hammett, M., Liu, W., Owen, D., Adesina, A., Fisher, K., Gluba, W., Ryan, A. B., Cronin, C., Scrable, H., & Seymour, L. (2013). Development of a positive-readout mouse model of siRNA pharmacodynamics. Molecular Therapy — Nucleic Acids, 2, e133.
  • Ryan, A. B. & Scrable, H. (2008) Mutant alleles of HD improve the life span of p53-/- mice. Mechanisms of Ageing and Development, 4, 238–241.
  • Ryan, A. B., Zeitlin, S., & Scrable, H. (2006) Genetic interaction between expanded Hdh alleles and p53 in the mouse reveal the deleterious effects of p53 on Huntington’s Disease pathogenesis. Neurobiology of Disease, 24
  • Ryan, A. B., & Scrable, H. (2004) Visualization of the dynamics of gene expression in the living mouse. Molecular Imaging, 3, 33–41.
  • Cronin, C. A., Ryan, A. B., Talley, E. M., & Scrable, H. (2003) Tyrosinase expression during neuroblast divisions affects later pathfinding by retinal ganglion cells. Journal of Neuroscience. 23, 1692–11697.
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